Brief CV

Field

Analytical Chemistry (Chromatographic techniques- Electroanalytical techniques- Sample pretreatment method- Chemometrics)

Studies

Diploma in Chemical Engineering, National Technical University of Athens (1999)

BSc in Pharmacy, Department of Pharmacy, National and Kapodistrian University of Athens, Greece (2004)

Ph.D.in  Analytical Chemistry, Laboratory of Inorganic and Analytical Chemistry, School of Chemical Engineering, National Technical University of Athens (2007)

Current Research Interests

• Biomimetic chromatographic techniques for the evaluation of pharmacokinetic properties (e.g. human oral absorption, protein binding, volume of distribution) and toxicological profile of candidate drugs as well as ecotoxicological profile of environmental pollutants (e.g. pesticides).
• Development of analytical methods for the detection and quantification of adulteration of foodstuffs (e.g. honey, olive oil) and identification of their geographical origin.

Selected Publications

• Tsopelas, T. Vallianatou, A. Tsantili- Kakoulidou, Recent developments in the application of immobilized artificial membrane (IAM) chromatography to drug discovery, Expert Opinion on Drug Discovery 19 (2024) 1087-1098.
• Liveri, A. Tsantili- Kakoulidou, F. Tsopelas, Identification of white wine adulteration with apple juice and apple cider using cyclic voltammetry on a screen-printed electrode aided by chemometric analysis, Journal of Food Composition and Analysis 136 (2024) 106751.
• Lymperopoulou, K. Balta- Brouma, L.A. Tsakanika, C. Tzia, A. Tsantili- Kakoulidou, Identification of lentils (Lens culinaris Medik) from Eglouvi (Lefkada, Greece) based on rare earth elements profile combined with chemometrics, Food Chemistry 447 (2024) 138965.
• Vallianatou, F. Tsopelas, A. Tsantili- Kakoulidou, Prediction Models for Brain Distribution based on biomimetic chromatographic data, Molecules 27 (2022) 3668.
• Tsopelas, P. Danias, A. Pappa, A. Tsantili-Kakoulidou, Biopartitioning micellar chromatography under different conditions: Insight into the retention mechanism and the potential to model biological processes, Journal of Chromatography A 1621 (2020) 461027.
• Nikolaou, E. Deskoulidis, E. Topoglidis, A. Tsantili- Kakoulidou, “Application of chemometrics for detection and modeling of adulteration of fresh cow milk with reconstituted skim milk powder using voltammetric fingerprinting on a graphite/ SiO₂ hybrid electrode”, Talanta 206 (2020) 120223.
• Stergiopoulos, D. Makarouni, A. Tsantili- Kakoulidou, M. Ochsenkühn- Petropoulou, F. Tsopelas, “Immobilized artificial membrane chromatography as a tool for the prediction of ecotoxicity of pesticides”, Chemosphere 224 (2019) 128-139.
• Tsopelas, D. Konstantopoulos, A. Tsantili- Kakoulidou, “Voltammetric fingerprinting of oils and its combination with chemometrics for the detection of extra virgin olive oil adulteration”, Analytica Chimica Acta 1015 (2018) 8-19.
• Tsopelas, C. Stergiopoulos, L.A. Tsakanika, M. Ochsenkühn- Petropoulou, A. Tsantili- Kakoulidou, “The use of immobilized artificial membrane chromatography to predict bioconcentration of pharmaceutical compounds”, Ecotoxicology and Environmental Safety 139 (2017) 150-157.
• Tsopelas, C. Giaginis, A. Tsantili- Kakoulidou, “Lipophilicity and biomimetic properties to support drug discovery”, Expert Opinion on Drug Discovery 12 (2017) 885-896.
• Tsopelas, Th. Vallianatou, A. Tsantili- Kakoulidou, “The potential of immobilized artificial membrane chromatography to predict human oral absorption”, European Journal of Pharmaceutical Sciences 81 (2016) 82-93.