Organic Chemistry

5276Mandatory

Course Description

The course material is part of the field of Basic Organic Chemistry and has as its main objective the study of the structure and reactions of organic molecules.

In particular, the topics covered in the lectures fall into the following areas: (i) Organic molecules structure and reactions: how to form bonds in carbon compounds, stereochemistry and reaction classes of organic compounds. (ii) Alkanes: structure, activity and characteristic reaction of alkanes (free radical substitution), cycloalkanes (structure, conformational analysis and reactions). (iii) Alkenes: alkene structure, mechanism of electrophilic addition reaction, elimination reactions (alcohol dehydration, dehydrohalogenation of alkyl halides, mechanisms E1, E2). (iv) Alkynes: structure and activity of alkynes, keto-enol tautomerism, acidity of alkynes. (v) Conjugated dienes: structure, activity and reactions of conjugated dienes (1,2- and 1,4- addition). (vi) Aromatic compounds: aromatic character, benzene structure and characteristic reaction (electrophilic aromatic substitution). (vii) Alkyl halides: structure and activity of alkyl halides, nucleophilic substitution reactions (SN1 & SN2 mechanisms). (viii) Alcohols: preparation reactions, physical and chemical properties of alcohols, mechanisms of characteristic reactions of alcohols. (ix) Ethers and epoxides: preparation reactions and mechanisms of characteristic ether and epoxide reactions. (x) Aldehydes and ketones: aldehyde and ketone preparation reactions, carbonyl addition reactions, activity of the α -hydrogen and condensation reactions. (xi) Carboxylic acids and their derivatives: preparation reactions and physicochemical properties of carboxylic acids and their derivatives (acid chlorides, anhydrides, esters, amides) as well as their physicochemical properties. (xii) Carboxylic Acid Derivatives: nucleophilic acyl substitution reactions. (xiii) Characteristic reactions of carbonyl compounds: mechanisms of characteristic reactions (name reactions) – e.g. Claisen condensation. (xiv) Amines: amines basicity, preparations and characteristic reactions of amines.

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