The course aims to introduce students to the field of pharmaceutical chemistry , the process of designing new drugs, the development of new formulations (drug delivery) and drug quality control. The course is tailored to the scientific fields of a Chemical Engineer, for whom the pharmaceutical industry is an important field of professional activity. At the same time, it provides essential knowledge for students interested in specializing in pharmaceutical chemistry and technology at a master’s level.

The course includes topics on: Introduction to Pharmaceutical Chemistry and Technology. Pharmacodynamic and pharmacokinetic data. Classification of drugs into major categories according to their pharmacological action (anti-inflammatory, analgesic, narcotic, cardiological, etc.). Chemistry of selected drug classes. Introduction to drug design. In silico methodologies. Biomimetic chromatography. Quantitative Structure-Action Relationships (QSAR). Development of formulations. Introduction to drug quality control. Laboratory exercises:  Synthesis of an active pharmaceutical ingredient. Preparation of formulations (cream and syrup). Encapsulation of bioactive molecule to Solid Lipid Nanoparticles. In vitro assay for enzyme inhibition. Physicochemical properties of drugs-determination of octanol-water partition coefficient.